Author

Wai Hang Cheng

University of British ColumbiaORCID 0000-0002-3408-9184Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Research Focus:cell type annotation· 2 Assay:electronic health records· 1 Assay:spatial transcriptomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Cheryl Lea WellingtoniD· 4 shared Jianjia Fan· 4 shared Carlos Barrón· 3 shared Honor CheungiD· 2 shared Jefferey YueiD· 2 shared Mehwish Anwer· 2 shared Peter A. CriptoniD· 2 shared Amy Kang· 1 shared

Activity by Year

2022-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersNeuroscience

Cheryl Lea WellingtonORCID

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4 papers

Recent·Most cited

NeuroscienceJournal of NeurotraumaPeer-reviewedMar 15, 2026

Repetitive mild traumatic brain injury causes neuronal damage in the APP/PS1 mouse model of Alzheimer's disease without an enduring impact on amyloid pathology, sleep, or epileptiform activity

Jefferey Yue, Victoria Carriquiriborde, Wai Hang Cheng…·Brianne A. Kent

1 citation

mouseelectronic health records

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NeurosciencebioRxivPreprintMay 23, 2025

Both the low-density lipoprotein receptor and apolipoprotein E define blood-borne high-density lipoprotein entry into the brain.

Sofia Kakava, Mary Gonzalez Melo, Wai Hang Cheng…·Jérôme Robert

The paper investigates how high-density lipoproteins (HDL) cross the blood-brain barrier, showing that LDLR and apoE composition determine HDL entry and brain localization.

DOI 10.1101/2025.05.23.655828

mouseexperimental assay

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NeurosciencebioRxivPreprintApr 27, 2023

Leveraging the power of 3D brain-wide imaging and mapping tools for brain injury research in murine models

Mehwish Anwer, Jeffrey M. LeDue, Zefang Wang…·Cheryl Lea Wellington

The paper describes a whole-brain imaging pipeline to study neuronal activity changes after traumatic brain injury in mice, finding reduced c-Fos cell density in injured brains.

1 citation

mousespatial transcriptomics

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NeurosciencebioRxivPreprintSep 1, 2022

Altered tau in rTg4510 mice after a single interfaced CHIMERA traumatic brain injury

Wai Hang Cheng, Honor Cheung, Amy Kang…·Cheryl Lea Wellington

This study examines the effects of a single moderate-severe TBI in rTg4510 mice using CHIMERA, finding divergent tauopathy and autophagolysosome responses in surviving mice.

DOI 10.1101/2022.09.01.506145

mouseexperimental assay

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