Photomechanical engineering of immunogenic whole-cell vaccines by laser-induced vapor nanobubbles for bladder cancer prophylaxis
Nuria Sabando-Garcia, Ainhoa G. Caelles, Noemi Traba, Joan Pages, Cecilia Cabrera, Anna Garcia Hidalgo, Deep Punj, Kevin Braeckmans, Annabel F. Valledor, Gertruda Chomiciute, Ibane Abasolo, Esther Julian, Samuel Sanchez, Juan C. Fraire
This paper demonstrates a drug-free method using laser-induced vapor nanobubbles to create immunogenic whole-cell vaccines for bladder cancer, showing reduced tumor growth and immune activation.
bioRxiv · Nov 9, 2026 · PreprintImmunology