Sequencing by avidity enables high accuracy with low reagent consumption
Sinan Arslan, Francisco J. Garcia, Minghao Guo, Matthew William Kellinger, Semyon Kruglyak, Jake A. LeVieux, Adeline Mah, Haosen Wang, Junhua Zhao, Chunhong Zhou, Andrew Altomare, John Bailey, Matthew B. Byrne, Chiting Chang, Steve X. Chen, , Jordan M. Neysmith
This paper introduces avidity sequencing, a new chemistry that improves sequencing accuracy and reduces reagent use, enabling applications like single-cell RNA-seq and whole-genome sequencing.
Nature Biotechnology · May 25, 2023Peer-reviewedGenomics