Author

Jake A. LeVieux

Elements Biosciences (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:benchmarking· 1 Assay:CRISPR screen· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Research Focus:perturbation response prediction· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew Altomare· 2 shared Bryan R. LajoieiD· 2 shared Daniel J. HonigfortiD· 2 shared Mariam Dawood· 2 shared Matthew William Kellinger· 2 shared Semyon KruglyakiD· 2 shared Sinan ArslaniD· 2 shared Adam Fries· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersGenomics

Andrew Altomare

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Author profile →

2 papers

Recent·Most cited

Direct In-Sample Sequencing of the 3' Transcriptome Expands the Capabilities of Optical Pooled Screens

Daniel J. Honigfort, Pedro Belda‐Ferre, David T. White, Kousik Sundararajan, Mariam Dawood, Jake A. LeVieux, Jacob Moreno, Xiaodong Qi, Kyle S. Metcalfe, Duuluu Naranbat, Andrew Altomare, Connor Thompson, Carlos Ruiz Perez, Bryan R. Lajoie, Hyuk-Jin Kwon, , Michael J. R. Previte

The paper introduces a platform that directly sequences 3'UTRs and guide RNAs in fixed cells alongside protein abundance and morphology, enabling CRISPR screening in lung cancer cells.

bioRxiv · Oct 11, 2025 · PreprintGenomics

Sequencing by avidity enables high accuracy with low reagent consumption

Sinan Arslan, Francisco J. Garcia, Minghao Guo, Matthew William Kellinger, Semyon Kruglyak, Jake A. LeVieux, Adeline Mah, Haosen Wang, Junhua Zhao, Chunhong Zhou, Andrew Altomare, John Bailey, Matthew B. Byrne, Chiting Chang, Steve X. Chen, , Jordan M. Neysmith

This paper introduces avidity sequencing, a new chemistry that improves sequencing accuracy and reduces reagent use, enabling applications like single-cell RNA-seq and whole-genome sequencing.

Nature Biotechnology · May 25, 2023Peer-reviewedGenomics