Junhua Zhao

Cytos MPS integrates CRISPR guide identity, morphology, transcriptomics, and protein data to reveal multimodal phenotypes from perturbations.

This paper introduces a simplified hybrid capture method that eliminates PCR and bead-based steps while maintaining specificity and improving variant calling.

This study compares Element Avidity sequencing to Illumina sequencing, finding higher accuracy in mapping and variant calling, especially at lower coverages and in challenging genomic regions.

This paper demonstrates high-quality, scalable human whole-genome sequencing on a benchtop sequencer, achieving 30x coverage with flexibility and cost-effectiveness.

The paper introduces iconPCR, a novel PCR technology that improves data quality and workflow by ensuring uniform amplification across reactions, leading to more accurate microbial community analysis.

The paper demonstrates that AVITI and Illumina sequencing technologies equally capture sRNA and csRNA libraries from human, cattle, and bison, revealing inaccuracies in genome annotations and highlighting the need for small RNA sequencing in livestock.

This study compares the AVITI and Illumina sequencing chemistries for DNA and RNA short-read and long-read sequencing, finding AVITI has higher quality scores and lower error rates in short-read applications.

This study compares imputation accuracy between avidity sequencing and sequencing by synthesis, finding comparable performance with lower duplication rates in avidity sequencing.

This paper introduces avidity sequencing, a new chemistry that improves sequencing accuracy and reduces reagent use, enabling applications like single-cell RNA-seq and whole-genome sequencing.