Sex and genetic specific effects on behavioral, but not metabolic, responses to a high fat diet in heterogeneous stock rats
Aaron W. Deal, Andrew L. Thurman, Osborne Seshie, Alexandria Szalanczy, Angela Beeson, Mackenzie Cockerham, Ellen L Risemberg, Anne Lenzo, Noelle Ozimek, Carl D. Langefeld, William S. J. Valdar, Leah C. Solberg Woods
This study shows that high fat diet affects metabolic health similarly in male and female HS rats but only males show altered behavioral responses, with genetic factors influencing both outcomes.
bioRxiv · Mar 25, 2022 · PreprintGenetics