Dorsal striatal dopamine induces fronto-cortical hypoactivity and implies reduced anxiety and compulsive behaviors in rats
Agata Casado-Sainz, Frederik Gudmundsen, Simone Larsen Bærentzen, Denise Lange, Annemette Ringsted, Isabel Martinez Tejada, Siria Medina, Hedok Lee, Claus Svarer, Sune Høgild Keller, Martin Schain, Celia Kjærby, Patrick M. Fisher, Paul D. Cumming, Mikael Palner
The paper investigates the effects of dorsal striatal dopamine activation on CSTC circuit function in rats, finding reduced fronto-cortical activity and changes in behaviors related to anxiety and compulsive actions.
bioRxiv · Feb 11, 2021 · PreprintNeuroscience