Selection of Candida albicans Trisomy during Oropharyngeal Infection Results in a Commensal-Like Phenotype
Anja Forche, Norma V. Solis, Marc Swidergall, Robert Thomas, Alison Guyer, Annette Beach, Gareth A. Cromie, Giang T. Le, Emily Lowell, Norman Pavelka, Judith G. Berman, Aimée M. Dudley, Anna M. Selmecki, Scott G. Filler
The paper shows that trisomy of chromosomes 5 or 6 in Candida albicans during oropharyngeal infection leads to a commensal-like phenotype with reduced virulence.
PLoS Genetics · May 15, 2019Peer-reviewedGenomics