Alison Guyer

This study develops optogenetic tools to control Nodal signaling patterns in zebrafish embryos, enabling precise spatial manipulation of signaling activity and rescue of developmental defects.

This study investigates how de novo proteins in yeast integrate into cellular systems using ancient targeting and degradation pathways, revealing a conserved molecular signature that enables their ER localization and regulation.

The paper shows that trisomy of chromosomes 5 or 6 in Candida albicans during oropharyngeal infection leads to a commensal-like phenotype with reduced virulence.