Competitive modulation of Kv1.2 gating by LMAN2 and Slc7a5
Damayantee Das, Shawn M. Lamothe, Anson A. Wong, Victoria A. Baronas, Harley T. Kurata
This study identifies Slc7a5 and LMAN2 as regulators of Kv1.2 channel gating, showing they compete for interaction with the voltage sensor, leading to complex voltage-dependent behavior.
The FASEB Journal · Dec 11, 2024Peer-reviewedBiophysics