Spatial Distribution of Missense Variants within Complement Proteins Associates with Age Related Macular Degeneration
Michelle A. Grunin, Sarah de Jong, Ellen L. Palmer, Bowen Jin, David C. Rinker, Christopher W. Moth, Anthony Capra, Jonathan L. Haines, William S. Bush, Anneke I. den Hollander, IAMDGC
The paper analyzes missense variants in complement genes to identify spatial associations with AMD risk using structural and functional metrics.
medRxiv · Aug 28, 2023 · PreprintGenetic & Genomic Medicine