Author

Bowen Jin

Case Western Reserve UniversityORCID 0000-0003-1442-6259Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioinformatics· 1 Genetic & Genomic Medicine· 1 Genetics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:statistical model· 3 Research Focus:differential expression· 2 Assay:scRNA-seq· 1 Research Focus:variant effect prediction· 1 Assay:whole-exome sequencing· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

William S. BushiD· 3 shared Jonathan L. HainesiD· 2 shared Adam Christian NajiD· 1 shared Anneke I. den HollanderiD· 1 shared Anthony Capra· 1 shared Badri Vadarajan· 1 shared Brian W. KunkleiD· 1 shared Christopher W. MothiD· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersGenetic & Genomic Medicine

William S. BushORCID

Mutual co-authors in cluster

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3 papers

Recent·Most cited

Genetic & Genomic MedicinemedRxivPreprintAug 28, 2023

Spatial Distribution of Missense Variants within Complement Proteins Associates with Age Related Macular Degeneration

Michelle A. Grunin, Sarah de Jong, Ellen L. Palmer…·IAMDGC

The paper analyzes missense variants in complement genes to identify spatial associations with AMD risk using structural and functional metrics.

DOI 10.1101/2023.08.28.23294686

humanwhole-genome sequencing

𝕏 PostBluesky

GeneticsbioRxivPreprintSep 21, 2022

Allelic Transcription Factor binding shape transcriptional kinetics observed with scRNA-seq in human cell lines

Bowen Jin, Hao Feng, William S. Bush

The paper investigates how allelic transcription factor binding influences transcriptional kinetics in human cell lines using scRNA-seq, finding strong correlations between eQTL effect sizes and burst frequency.

DOI 10.1101/2022.09.21.508743

𝕏 PostBluesky

BioinformaticsGenome ResearchPeer-reviewedApr 1, 2022

An Association Test of the Spatial Distribution of Rare Missense Variants within Protein Structures Improves Statistical Power of Sequencing Studies

Bowen Jin, John A. Capra, Penelope H. Benchek…·William S. Bush

POKEMON improves statistical power for detecting associations between rare missense variants and phenotypes by analyzing their spatial distribution on protein structures.

6 citations

humanwhole-exome sequencing

𝕏 PostBluesky