Author
AbbVie (United States)ORCID 0000-0003-0634-5408Unclaimed ORCID profile · follow to get notified of new preprints
Mutual co-authors in cluster
8 papers
Recent·Most cited
Caitlin E. Purman, Charles Lu, Apexa Modi…·Joshua D. Stender
The paper introduces DICE, a CRISPR screening method that improves scalability and robustness over SLICE in THP1 cells by using dual-guide RNA infection with Cas9 electroporation.
Samaneh Farashi, Carla J. Abbott, Brendan R. E. Ansell…·Melanie Bahlo
Fedik Rahimov, Sujana Ghosh, Sakina M. Petiwala…·Joshua D. Stender
A genome-wide CRISPR screen and genetic analysis identify TNRC18 as a novel regulator of IL-1β production and a risk factor for inflammatory diseases.
Michelle A. Grunin, Sarah de Jong, Ellen L. Palmer…·IAMDGC
The paper analyzes missense variants in complement genes to identify spatial associations with AMD risk using structural and functional metrics.
Minna K. Karjalainen, Savita Karthikeyan, Clare Oliver‐Williams…·Johannes Kettunen
This study identifies 400+ genetic loci associated with circulating metabolic traits and highlights pleiotropy and novel disease pathways.
Rebekkah J. Hitti‐Malin, Claire‐Marie Dhaenens, Daan M. Panneman…·Frans P.M. Cremers
The paper uses smMIPs to sequence MD-associated genes and loci in patients, achieving high coverage and a 38% diagnostic yield.
Jonas J. W. Kuiper, Jessica van Setten, Matthew A.M. Devall…·Timothy R. D. J. Radstake
This study identifies functionally distinct ERAP1 and ERAP2 haplotypes associated with Birdshot Uveitis and shows their combined effect enhances disease risk.
Anne‐Mieke J. W. Haasnoot, MW Schilham, Sylvia S M Kamphuis…·Jonas J. W. Kuiper
The paper identifies serine-11 in HLA-DRB1 as a risk factor for uveitis in JIA, showing sex-specific association and peptide-binding preferences.