GABAergic LRP1 is a key link between obesity and memory function
Aykut Göktürk Üner, Zhi-Shuai Hou, Ahmet Aydogan, KELLEN RODRIGUES, Jennie Young, Anthony Choi, Won‐Mo Yang, Woojin Scott Kim, Vincent Prévot, Barbara J. Caldarone, Bradley T. Hyman, Hyon Lee, Young‐Bum Kim
This study shows that deleting LRP1 in GABAergic neurons causes memory impairments and obesity in mice, linking LRP1 function to metabolic and cognitive health.
bioRxiv · Sep 17, 2022 · PreprintNeuroscience