Visual Cell Sorting: A High-throughput, Microscope-based Method to Dissect Cellular Heterogeneity
Nicholas Hasle, Anthony Cooke, Sanjay R Srivatsan, Heather Z Huang, Jason J. Stephany, Zachary Krieger, Dana L. Jackson, Weiliang Tang, Sriram Pendyala, Raymond J. Monnat, Cole Trapnell, Emily M. Hatch, Douglas M. Fowler
This paper introduces a method to physically separate live cells based on visual phenotypes and uses it to study nuclear localization sequences and paclitaxel resistance in human cancers.
bioRxiv · Dec 9, 2019 · PreprintMolecular Biology