Building synthetic chromosomes from natural DNA
Alessandro Luis Venega Coradini, Christopher Ne Ville, Zachary Krieger, Joshua Roemer, Cara B. Hull, Shawn Yang, Daniel T. Lusk, Ian M. Ehrenreich
This paper introduces CReATiNG, a method to build synthetic chromosomes from natural DNA in yeast, enabling chromosome recombination, modification, and deletion of non-adjacent regions.
Nature Communications · Dec 20, 2023Peer-reviewedSynthetic Biology