Role Of The Membrane Cholesterol-Glycosphingolipid Complex As A Transistor To Regulate GSL Receptor Function And Signaling Of Both Lipids
Anton Novak, Clifford Lingwood
The paper shows cholesterol and glycosphingolipids (GSL) form a complex that masks ligand binding sites, acting as a biological transistor to regulate GSL receptor signaling and antibody efficacy.
bioRxiv · May 13, 2017 · PreprintCell Biology