ImmunologybioRxivPreprint
Autoinflammatory patients with Golgi-trapped CDC42 exhibit intracellular trafficking defects leading to STING hyperactivation
Alberto Iannuzzo, Selket Delafontaine, Rana El Masri…·Jérôme Delon
This study identifies Golgi-trapped CDC42 variants causing STING hyperactivation and IFN elevation in autoinflammatory patients.
DOI 10.1101/2024.01.31.578189