A general role for GGA adaptors in the modulation of AP-1-dependent trafficking
Alexander Stockhammer, Antonia Klemt, Aline Dominique Daberkow, Jelena Mijatovic, Laila Sofie Benz, Christian Freund, Benno Kuropka, Francesca Bottanelli
This study investigates the role of GGAs in AP-1-dependent trafficking using CRISPR-Cas9 and live-cell imaging, finding GGAs modulate bi-directional trafficking by preventing AP-1 cargo retrieval.
bioRxiv · Mar 26, 2026 · PreprintCell Biology