The antimycotic 5-fluorocytosine is a virulence inhibitor of uropathogenic Escherichia coli and eradicates biofilm-embedded bacteria synergizing with β-lactams
Srikanth Ravishankar, Antonietta Lucia Conte, Stacy Julisa Carrasco Aliaga, Valerio Baldelli, Karen Leth Nielsen, Moira Paroni, Maria Pia Conte, Paolo Landini, Elio Rossi
This paper shows that 5-fluorocytosine inhibits biofilm formation and virulence in uropathogenic E. coli and synergizes with β-lactams to eradicate biofilm-embedded bacteria.
Antimicrobial Agents and Chemotherapy · Apr 4, 2025Peer-reviewedMicrobiology