Primary Somatosensory Cortex Bidirectionally Modulates Sensory Gain and Nociceptive Behavior in a Layer-Specific Manner
Katharina Ziegler, Ross Folkard, Antonio J. Gonzalez, Jan Burghardt, Sailaja Antharvedi-Goda, Jesús Martín-Cortecero, Emilio Ulises Isaías-Camacho, Sanjeev Kumar Kaushalya, Linette Liqi Tan, Thomas Kuner, Claudio Acuna, Rohini Kuner, Rebecca Audrey Mease, Alexander Groh
This study shows that layer 5 and 6 neurons in the primary somatosensory cortex modulate sensory gain and nociceptive behavior in opposite ways.
Nature Communications · May 24, 2023Peer-reviewedNeuroscience