Thomas Kuner

This study proposes a dual-ensemble model of infralimbic cortex function in behavioural flexibility, showing that IL activity dynamically encodes predictive accuracy through action-outcome prediction and prediction correction.

The paper characterizes thalamocortical projections from higher-order thalamic nuclei using retrograde tracing and a neural network-based pipeline, revealing repetitive anatomical patterns in projection strength and spatial organization.

Glyco-STORM maps nanoscale glycosylation patterns in cells, revealing subcellular glycan domains and a spatial glycosylation code.

This paper introduces a tactile discrimination task for freely moving mice, combining electrophysiology and calcium imaging to study neuronal dynamics during learning and behavior.

The paper identifies glucocorticoid receptor-mediated astrocyte reprogramming in depression using post-mortem samples and mouse models.

This study identifies a thalamo-amgydalar circuit dysfunction caused by early-life adversity that contributes to chronic pain and anxiety in female mice.

This study shows that layer 5 and 6 neurons in the primary somatosensory cortex modulate sensory gain and nociceptive behavior in opposite ways.

The paper identifies neuronal loss in the secondary motor cortex as a mechanism underlying chronic neuropathic pain using longitudinal in vivo imaging.

The paper introduces 3MDR, a device for EMDR-like visual stimulation in mice, showing that alternating bilateral stimuli reduce fear and that effects depend on stimulus brightness.

The paper introduces NuCLear, a method combining in vivo two-photon imaging and deep learning to monitor tissue composition over time in mice brains.

The paper correlates grey matter volume changes with cellular metrics in mice using MRI and in vivo imaging.

The paper introduces maS3TORM, a method for highly multiplexed 3D super-resolution imaging of proteins in cells and tissues, achieving sub-10 nm localization precision for up to 16 targets.

The paper shows that glomerular odor representations' similarity and activation strength determine the time needed for odor discrimination, independent of sniffing behavior.

RetroLEAP enables retrograde trans-synaptic labeling, expression, and perturbation of neurons using a GFP-dependent recombinase system.

This study shows that acute ethanol intoxication causes loss of presynaptic boutons without mitochondria in mice, potentially explaining memory impairments.

The paper visualizes and quantifies dense core vesicle (DCV) trafficking in axons of anesthetized and awake mice, finding faster maximal speeds and lower pausing fraction in vivo compared to in vitro studies.

The paper measures intracellular chloride concentration and pH in cortical neurons of mice under anesthesia and wakefulness, finding KCC2 is essential for maintaining low [Cl-]i.