Author

Antonio Rosato

Istituto Oncologico Veneto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Biology Disciplines

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Synthetic Biology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Álvaro Muñoz‐LópeziD· 2 shared Anna Urbanetz· 2 shared Boris EngelsiD· 2 shared Charlotte U. ZajciD· 2 shared Daniel MareschiD· 2 shared Dominik EmmingeriD· 2 shared Elise SylvanderiD· 2 shared Fabian EngertiD· 2 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersSynthetic Biology

Álvaro Muñoz‐LópezORCID

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2 papers

Recent·Most cited

Engineering human protein switches for functional control of CARs and transcription factors via oral drug administration

Elise Sylvander, Álvaro Muñoz‐López, Giulia D’Accardio, Dominik Emminger, Konstantina Mouratidis, Fabian Engert, Hayeon Baik, Sanjana Balaji, Theresa Michls, Michelle C. Buri, Daniel Maresch, Anna Urbanetz, Markus Schäfer, Joerg Mittelstaet, Johannes A. Zuber, , Manfred Lehner

This paper describes the engineering of a molecular switch that controls CARs and transcription factors using an orally available drug, demonstrating tight regulation in vitro and in vivo.

bioRxiv · Oct 17, 2025 · PreprintSynthetic Biology

Caffeine-regulated molecular switches for functional control of CAR T cells in vivo

Elise Sylvander, Benjamin Salzer, Dominik Emminger, Hayeon Baik, Giulia D’Accardio, Markus Schäfer, Konstantina Mouratidis, Michelle C. Buri, Daniel Maresch, Anna Urbanetz, Jacqueline Seigner, Elisa Marchiori, Álvaro Muñoz‐López, Fabian Engert, Boris Engels, , Michael W. Traxlmayr

This paper develops caffeine-responsive switches for CAR T cells, showing they can be controlled by caffeine and effectively clear tumors in mice.

bioRxiv · Jun 13, 2025 · PreprintSynthetic Biology