FINCA disease mouse model exhibits altered behaviour and immune response
Anniina E. Hiltunen, Salla M. Kangas, Aishwarya Gondane, Henna Koivisto, Kari Salokas, Anne Heikkinen, Antti M. Salo, Tapio Röning, Antti Tallgren, Virpi Glumoff, Maria C. Denis, Niki Karagianni, Johanna Myllyharju, Markku T Varjosalo, Heikki Tanila, , Reetta Hinttala
The paper describes a FINCA mouse model with mild hyperactivity and altered immune response, identifying Rho GTPase signaling as a key pathway affected by the p.Asp148Tyr variant in NHLRC2.
Brain Behavior & Immunity - Health · May 22, 2025Peer-reviewedNeuroscience