Author

Henna Koivisto

University of Eastern Finland

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Neuroscience· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell-cell communication· 1 Assay:metabolomics· 1

Frequent Co-Authors

Heikki TanilaiD· 3 shared Anne HeikkineniD· 2 shared Antti M. SaloiD· 2 shared Johanna UusimaaiD· 2 shared Reetta HinttalaiD· 2 shared Aishwarya GondaneiD· 1 shared Alfredo Ramı́reziD· 1 shared Annakaisa HaapasaloiD· 1 shared

Activity by Year

2024-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersNeuroscience

Heikki TanilaORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Novel Cln8 p.R24G mouse line replicates major clinical features of Northern epilepsy

Jessica Müller-Niva, Antti M. Salo, Sara Häkli, Irina Gureviciene, Anthi‐Styliani Makiou, Henna Koivisto, Harri P. Elamaa, Ilkka Miinalainen, Anne Heikkinen, Lauri Eklund, Petra Sipilä, Satu Kuure, Henri Leinonen, Johanna Uusimaa, Heikki Tanila, Reetta Hinttala

This paper generates a Cln8 p.R24G mouse model that phenocopies major clinical features of Northern epilepsy, including seizures and neurodegeneration.

bioRxiv · Dec 5, 2025 · PreprintNeuroscience

FINCA disease mouse model exhibits altered behaviour and immune response

Anniina E. Hiltunen, Salla M. Kangas, Aishwarya Gondane, Henna Koivisto, Kari Salokas, Anne Heikkinen, Antti M. Salo, Tapio Röning, Antti Tallgren, Virpi Glumoff, Maria C. Denis, Niki Karagianni, Johanna Myllyharju, Markku T Varjosalo, Heikki Tanila, , Reetta Hinttala

The paper describes a FINCA mouse model with mild hyperactivity and altered immune response, identifying Rho GTPase signaling as a key pathway affected by the p.Asp148Tyr variant in NHLRC2.

Brain Behavior & Immunity - Health · May 22, 2025Peer-reviewedNeuroscience

Protective variant in PLCgamma2 mitigates Alzheimer's disease associated pathology via enhancing beneficial microglia functions

Mari Takalo, Heli Jeskanen, Taisia Rõlova, Inka Kervinen, Marianna Hellén, Sami Heikkinen, Henna Koivisto, Kimmo T. Jokivarsi, Stephan A. Müller, Esa-Mikko Koivumäki, Petra M. Mäkinen, Sini-Pauliina Juopperi, Roosa-Maria Willman, Rosa Sinisalo, Dorit Hoffman, , Mikko Hiltunen

This study shows that the PLCgamma2-P522R variant reduces beta-amyloid pathology and enhances microglial function in AD models, suggesting an anti-ageing mechanism.

bioRxiv · Sep 12, 2024 · PreprintNeuroscience