DNA Methyltransferase 1 and 3a Expression in the Frontal Cortex Regulates Palatable Food Consumption
Mohan C. Manjegowda, Jonathan Joy-Gaba, Eric R. Wengert, Anusha U. Saga, Daniel M. Warthen, Amelie Kuchler, Ronald Petrus Albertus Gaykema, Manoj K. Patel, Nathan C. Sheffield, Michael M. Scott
This study shows that deleting DNA methyltransferase 1 and 3a in the mouse prefrontal cortex reduces palatable food consumption without affecting chow intake, with effects on neuron excitability and DNA methylation patterns.
bioRxiv · May 23, 2021 · PreprintNeuroscience