Immune signatures of protection and progression in the airways of recent human tuberculosis household contacts
William J. Branchett, Jee-Whang Kim, Jessica Shields, Probir Chakravarty, Jo Lee, Ismail Novsarka, Hubert Slawinski, Katalin Andrea Wilkinson, Robert John Wilkinson, Anver Kamil, Raman Verma, Pranabashis Haldar, Anne O’Garra
The paper identifies immune signatures in TB contacts that predict protection or progression to active TB using single-cell RNA sequencing and correlates findings with non-human primate data.
Nature Immunology · Jun 24, 2026Peer-reviewedImmunology