Author

Katalin Andrea Wilkinson

University of Cape TownORCID 0000-0002-9796-2040Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Approach:statistical model· 2 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

Robert John WilkinsoniD· 3 shared Anne O’GarraiD· 2 shared Graeme MeintjesiD· 2 shared Hubert SlawinskiiD· 2 shared Abulele BekiswaiD· 1 shared Alize M ProustiD· 1 shared Angharad DavisiD· 1 shared Anver Kamil· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersImmunology

Robert John WilkinsonORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Immune signatures of protection and progression in the airways of recent human tuberculosis household contacts

William J. Branchett, Jee-Whang Kim, Jessica Shields, Probir Chakravarty, Jo Lee, Ismail Novsarka, Hubert Slawinski, Katalin Andrea Wilkinson, Robert John Wilkinson, Anver Kamil, Raman Verma, Pranabashis Haldar, Anne O’Garra

The paper identifies immune signatures in TB contacts that predict protection or progression to active TB using single-cell RNA sequencing and correlates findings with non-human primate data.

Nature Immunology · Jun 24, 2026Peer-reviewedImmunology

Contribution of cytotoxic CD8 T cells, neutrophils and type 1 interferon signaling to hyperinflammation in HIV-associated TB meningitis

James R. Barnacle, Nonzwakazi Bangani, Hubert Slawinski, Christopher Barrington, Katalin Andrea Wilkinson, Cari J. Stek, Rachel Lai, Fabrice Bonnet, Graeme Meintjes, Brian D. Robertson, Martin Gengenbacher, Angharad Davis, Daniel L. Barber, Anne O’Garra, Robert John Wilkinson

This study identifies a hyper-inflammatory immune response in HIV-associated TB meningitis, marked by cytotoxic CD8 T cells, activated neutrophils, and type 1 interferon signaling.

bioRxiv · Mar 23, 2026 · PreprintImmunology

M. tuberculosis invades and disrupts the blood-brain barrier directly to initiate meningitis

Alize M Proust, Katalin Andrea Wilkinson, Robert John Wilkinson

This study shows M. tuberculosis can directly cross the blood-brain barrier and cause meningitis, with HIV-1 enhancing bacterial entry and BBB disruption.

Journal of Neuroinflammation · May 26, 2025Peer-reviewedMicrobiology

Two distinct cytokine response clusters identified in healthcare workers with apparent resistance to infection with Mycobacterium tuberculosis despite sustained occupational exposure

Avuyonke Balfour, Nomawethu Masina, Artur T. L. Queiroz, Bruno B. Andrade, Eduardo Rocha Fukutani, Abulele Bekiswa, David Michael Lewinsohn, Deborah A. Lewinsohn, Rene T. Goliath, Katalin Andrea Wilkinson, Charlotte Schutz, Graeme Meintjes, Muki Shehu Shey

The paper identifies two distinct cytokine response clusters in healthcare workers resistant to Mtb infection despite exposure, using cytokine profiling and clustering analysis.

bioRxiv · Mar 27, 2025 · PreprintImmunology