Dynamic remodeling of the pancreas immune landscape in obesity.
Alexey Koshkin, Kranthi Kiran Kishore Tanagala, Anna Eichinger, Michael Chait, Aoife Young, Shanila Shakil, Junichi Yoshikawa, Yosuke Sakamoto, Steven B. Wells, Ladan Fazlollahi, Xiaojuan Chen, Boris Reizis, Donna L. Färber, Stuart Phillip Weisberg
This study identifies how obesity alters the pancreatic immune landscape by shifting macrophage subsets and enhancing T-cell interactions, contributing to chronic inflammation.
Nature Communications · Jul 28, 2026Peer-reviewedImmunology