Boris Reizis

This study identifies how obesity alters the pancreatic immune landscape by shifting macrophage subsets and enhancing T-cell interactions, contributing to chronic inflammation.

This study shows cohesin-mediated chromatin remodeling is essential for dendritic cell differentiation and function, particularly antigen cross-presentation and IL-12 secretion.

DNA origami particles displaying eOD-GT8 with a synthetic T helper epitope gave antigen-focused germinal centers and expanded VRC01-class precursors in humanized mice after one immunization.

This study shows that IFNγ suppresses lymphatic vessel growth and metastasis by altering metabolism and immune function in melanoma.

This study maps the spatial and single-cell landscape of Castleman Disease, identifying key stromal cell types and cytokine pathways involved in disease pathology.

The paper introduces two batch alignment methods for single-cell RNA sequencing to address drop-out issues and improve clustering accuracy across batches.