Steven B. Wells

The paper presents the Human Gut Cell Atlas v1.0, a unified reference of gut cell diversity, revealing how tissue structure influences cellular composition and enabling disease and organoid analysis.

This study identifies how obesity alters the pancreatic immune landscape by shifting macrophage subsets and enhancing T-cell interactions, contributing to chronic inflammation.

dreampy implements the dreamlet framework for pseudobulk differential expression analysis in single-cell RNA-seq using Python.

The paper shows that NK cell responses to CMV infection differ between infants and adults, influenced by age and T cell immunity, with infant NK cells exhibiting adaptive-like features and tissue seeding.

This study identifies tissue-specific transcriptional and protein profiles of human macrophages in various organs during homeostasis and activation, showing homology to mouse macrophages and responsiveness to cytokine stimuli.

The paper profiles immune cell RNA and protein expression across tissues and age to identify tissue-specific and age-related immune signatures.

This paper introduces MMoCHi, a multimodal classifier for CITE-seq data that improves immune cell subset annotation by integrating transcriptomic and proteomic data.