Macrophage phagocytosis of Coccidioides promotes its differentiation into the parasitic form
Jane Symington, Apoorva Dabholkar, Bevin C. English, Mark Voorhies, Anita Sil
This study shows that macrophage phagocytosis of Coccidioides arthroconidia promotes their differentiation into spherules, a pathogenic form, through direct interaction rather than soluble factors.
mBio · May 18, 2026Peer-reviewedMicrobiology