Bevin C. English

This study optimizes conidial production in Histoplasma, identifying media and conditions that enhance conidiation and germination, and reveals strain-specific responses and cell wall composition differences.

This study shows that macrophage phagocytosis of Coccidioides arthroconidia promotes their differentiation into spherules, a pathogenic form, through direct interaction rather than soluble factors.

The paper shows that rapid gain and loss of chromosome seven in Histoplasma affects morphology, virulence, and environmental adaptation.

The paper identifies a large expansion of knottin genes in Histoplasma and shows their role in virulence and host cell lysis during macrophage infection.

This study shows that loss of neutrophil Shp1 causes severe lung injury and death in mice, and that activating Shp1 can reduce inflammation and lung damage.