BiochemistryJournal of Biological ChemistryPeer-reviewed
The BCKDK inhibitor BT2 is a chemical uncoupler that lowers mitochondrial ROS production and de novo lipogenesis
Aracely Acevedo, Anthony E. Jones, Bezawit T. Danna…·Ajit S. Divakaruni
The paper shows BT2 acts as a mitochondrial uncoupler, reducing ROS and lipogenesis, which may explain its therapeutic benefits in metabolic diseases.
32 citations