Lamin B loss in nuclear blebs is rupture dependent while increased DNA damage is rupture independent
Catherine G. Chu, Nick Lang, Erin Walsh, Ming Zheng, Gianna Manning, Kiruba Shalin, Lyssa M. Cunha, Kate E. Faucon, Nicholas Kam, Sara N. Folan, Arav P. Desai, Emily Naughton, Jaylynn Abreu, Alexis M. Carson, Zachary L. Wald, , Andrew D. Stephens
The paper measures lamin B and DNA damage in blebbed nuclei to determine the effect of nuclear rupture, finding lamin B loss is rupture-dependent while DNA damage is independent.
Journal of Cell Science · Oct 6, 2025Peer-reviewedCell Biology