Author

Catherine G. Chu

University of Massachusetts Amherst

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 2 Assay:imaging· 2 Research Focus:differential expression· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Andrew D. StephensiD· 3 shared Nick LangiD· 3 shared Gianna Manning· 2 shared Mai Pho· 2 shared Alexis M. Carson· 1 shared Andy Li· 1 shared Anish Shah· 1 shared Arav P. Desai· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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3 shared papersCell Biology

Andrew D. StephensORCID

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3 papers

Recent·Most cited

Lamin B1 affects nuclear shape and integrity through chromatin stiffness and not lamin stiffness

Andy Li, Catherine G. Chu, Nick Lang, Edward J. Banigan, Andrew D. Stephens

This study shows lamin B1 affects nuclear shape and integrity via chromatin stiffness, not lamin stiffness, using mechanical measurements and simulations.

bioRxiv · Aug 11, 2026 · PreprintCell Biology

Changes in nuclear and actin mechanics from G1 to G2 affect nuclear integrity

Samantha Bunner, Katie T. Huang, Anish Shah, Schuyler Figueroa, Nick Lang, Catherine G. Chu, Nebiyat Eskndir, Mai Pho, Gianna Manning, Mindy Zheng, Lillian K. Fritz‐Laylin, Katrina Velle, Joshua Marcus, James D. Orth, Andrew D. Stephens

This study shows that nuclear and actin mechanics change from G1 to G2, leading to decreased nuclear stiffness and increased vulnerability to rupture.

Journal of Cell Science · Jan 19, 2026Peer-reviewedCell Biology

Lamin B loss in nuclear blebs is rupture dependent while increased DNA damage is rupture independent

Catherine G. Chu, Nick Lang, Erin Walsh, Ming Zheng, Gianna Manning, Kiruba Shalin, Lyssa M. Cunha, Kate E. Faucon, Nicholas Kam, Sara N. Folan, Arav P. Desai, Emily Naughton, Jaylynn Abreu, Alexis M. Carson, Zachary L. Wald, , Andrew D. Stephens

The paper measures lamin B and DNA damage in blebbed nuclei to determine the effect of nuclear rupture, finding lamin B loss is rupture-dependent while DNA damage is independent.

Journal of Cell Science · Oct 6, 2025Peer-reviewedCell Biology