The La Crosse virus M segment determines virus isolate cell-to-cell spread and virulence
Molly V. Durawa, Nicole C. Rondeau, Sophie N. Spector, Sara A. Thannickal, Abbie E. Weight, Ariana Dedvukaj, Matthew C. Lutchko, Helen M. Lazear, Kenneth A. Stapleford
This study identifies the M segment of La Crosse virus as a key determinant of cell-to-cell spread, virulence, and plaque size across different viral isolates.
bioRxiv · Sep 20, 2026 · PreprintMicrobiology