Replication protein-A, RPA, plays a pivotal role in the maintenance of recombination checkpoint in yeast meiosis
Arivarasan Sampathkumar, Zhong Chen, Yuting Tang, Yurika Fujita, Masaru Ito, Akira Shinohara
This study shows RPA is essential for maintaining the meiotic recombination checkpoint in yeast by sensing ssDNA and activating Mek1 kinase to regulate pachytene exit.
Scientific Reports · Apr 25, 2024Peer-reviewedGenetics