Neurofilament Light Disordered Tail Mutations Reshape Its Self-Assembled Network Structure
Rawan Aodeh, Yoav Dan, Dean Yona, Mohammad Shalabi, Asaf Sivan, Mathar Kravicas, Hillel Aharoni, Gil Koren, Lihi Adler‐Abramovich, Roy Beck
The paper investigates how mutations in the disordered tail of neurofilament-light protein affect its self-assembled network structure and function, revealing mechanisms linking sequence changes to disease.
Journal of the American Chemical Society · Jul 21, 2026Peer-reviewedBiophysics