Author

Roy Beck

Tel Aviv UniversityORCID 0000-0003-3121-4530Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:human· 3 Approach:experimental assay· 2 Research Focus:protein folding & dynamics· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:long-read sequencing· 1 Assay:protein structure· 1

Frequent Co-Authors

Dean Yona· 3 shared Asaf Sivan· 2 shared Gil KoreniD· 2 shared Rawan AodehiD· 2 shared Aasaf Sivan· 1 shared Daniel Oliveros Gingerich· 1 shared Elliot Keats ShwabiD· 1 shared Geidy E. SerranoiD· 1 shared

Activity by Year

2025-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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3 shared papersBiophysics

Dean Yona

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3 papers

Recent·Most cited

Neurofilament Light Disordered Tail Mutations Reshape Its Self-Assembled Network Structure

Rawan Aodeh, Yoav Dan, Dean Yona, Mohammad Shalabi, Asaf Sivan, Mathar Kravicas, Hillel Aharoni, Gil Koren, Lihi Adler‐Abramovich, Roy Beck

The paper investigates how mutations in the disordered tail of neurofilament-light protein affect its self-assembled network structure and function, revealing mechanisms linking sequence changes to disease.

Journal of the American Chemical Society · Jul 21, 2026Peer-reviewedBiophysics

Not All Charges Are Equal: Side-Chain Chemistry Reshapes the Disordered Ensemble of α-synuclein

Gil Koren, Nuno Fernandes, Asaf Sivan, Rawan Aodeh, Dean Yona, Mathar Kravikass, Yuval Keidar, Kresten Lindorff‐Larsen, Roy Beck

This paper shows that arginine substitutions, despite similar charge, compact α-synuclein more than lysine, accelerating amyloid formation and reshaping its disordered ensemble.

bioRxiv · Jun 10, 2026 · PreprintBiophysics

Single cell transcriptomics reveals enrichment of aggregation-prone alpha-synuclein isoforms across synucleinopathies

Elliot Keats Shwab, Webb Pierson, Daniel Oliveros Gingerich, Zhaohui Man, Sapir Margalit, Dean Yona, Aasaf Sivan, Julia Gamache, Geidy E. Serrano, Thomas G. Beach, Yuval Ebenstein, Roy Beck, Ornit Chiba‐Falek

The paper uses long-read and single nucleus RNA-seq to identify novel SNCA transcript isoforms and their association with Parkinson's and Lewy body dementia.

bioRxiv · Oct 13, 2025 · PreprintNeuroscience