Endogenous CGRP activates NRF2 signaling via non-electrophilic mechanisms
Keren Powell, Steven Wadolowski, Willians Tambo, Eric H. Chang, Daniel J. Kim, Asha Jacob, Daniel Michael Sciubba, Yousef Al‐Abed, Ping Wang, Chunyan Li
This study shows endogenous CGRP activates NRF2 via non-electrophilic mechanisms, with organ-specific pathways and time-dependent effects on oxidative stress resistance.
bioRxiv · Apr 25, 2025 · PreprintMolecular Biology