Chunyan Li

This paper shows that artificial diving reflex via trigeminal nerve stimulation activates NRF2 through p62 phosphorylation, offering neuroprotection in traumatic brain injury without depleting antioxidant reserves.

This paper shows that trigeminal nerve stimulation reduces traumatic brain injury-induced neuronal damage by preserving mitochondrial function through the CGRP-PINK1 mitophagy pathway.

This study identifies vasoactive neuropeptide dysregulation as a key driver of microvascular dysfunction and cognitive decline in chronic cerebral hypoperfusion.

This study shows endogenous CGRP activates NRF2 via non-electrophilic mechanisms, with organ-specific pathways and time-dependent effects on oxidative stress resistance.

This study investigates how the diving reflex alleviates microvascular dysfunction and improves cognitive performance in a rat model of vascular cognitive impairment.

This study shows that both acute and chronic diving reflex activate NRF2 signaling, with acute exposure inducing stronger antioxidative gene expression than chronic exposure.