Ping Wang

This paper shows that artificial diving reflex via trigeminal nerve stimulation activates NRF2 through p62 phosphorylation, offering neuroprotection in traumatic brain injury without depleting antioxidant reserves.

This paper shows that trigeminal nerve stimulation reduces traumatic brain injury-induced neuronal damage by preserving mitochondrial function through the CGRP-PINK1 mitophagy pathway.

This study shows eCIRP induces neurotoxic astrocytes via TREM-1 in Alzheimer's disease, with M3 blocking this effect.

This study identifies huTLR8's role in placental defects and pregnancy loss in lupus mice, showing its involvement in immune dysregulation and inflammation.

This study identifies vasoactive neuropeptide dysregulation as a key driver of microvascular dysfunction and cognitive decline in chronic cerebral hypoperfusion.

This study shows endogenous CGRP activates NRF2 via non-electrophilic mechanisms, with organ-specific pathways and time-dependent effects on oxidative stress resistance.

This study shows that dopamine D4 receptor reduces NCC protein levels by promoting its ubiquitination and lysosomal degradation in mice.

This study evaluates urinary exosome NHE3 as a noninvasive biomarker for acute kidney injury (AKI) across multiple animal models and human patients, showing increased NHE3 levels in all tested AKI conditions.

This study shows that reducing CSF-2 in Csf1r+/- mice rescues behavioral and histopathological deficits in ALSP by preventing microgliosis and transcriptomic changes, suggesting CSF-2 as a therapeutic target.