Author

Ashraf Abdo

Columbia University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:trajectory inference· 1

Frequent Co-Authors

Moustafa Tarek GabriD· 2 shared Sungwoo ChoiD· 2 shared Baljit KauriD· 1 shared Hongliang DuaniD· 1 shared Yutong GeiD· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

5 top collaborators · 8 mutual co-author links

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2 shared papersPharmacology & Toxicology

Moustafa Tarek GabrORCID

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2 papers

Recent·Most cited

DNA-Encoded Library-Guided Discovery of a First-in-Class Molecular Glue of the NOS1AP-SCRIB Complex in Alzheimer's Disease Patient-Derived Neurons

Baljit Kaur, Ashraf Abdo, Sungwoo Cho, Moustafa Tarek Gabr

This paper identifies and optimizes a molecular glue that stabilizes the NOS1AP-SCRIB interaction, showing therapeutic effects in Alzheimer's patient-derived neurons.

bioRxiv · Oct 18, 2026 · PreprintPharmacology & Toxicology

A First-in-Class, Brain-Penetrant Small Molecule Inhibitor of the NOS1AP-Tau Interaction Rescues Tau Pathology In Vivo and Improves Cognition

Ashraf Abdo, Sungwoo Cho, Yutong Ge, Hongliang Duan, Moustafa Tarek Gabr

CAPTOR-1, a small molecule inhibitor of NOS1AP-tau interaction, reduces tau pathology and improves cognition in AD models.

bioRxiv · Oct 7, 2026 · PreprintPharmacology & Toxicology