Zebrafish optic nerve injury results in systemic retinal ganglion cell dedifferentiation
Ashrifa Ali, Hannah C. Schriever, Dennis Kostka, Takaaki Kuwajima, Kristen M. Koenig, Jeffrey M. Gross
This study shows that zebrafish retinal ganglion cells dedifferentiate after optic nerve injury, resembling immature RGCs, and identifies potential therapeutic targets for human RGC protection.
PLoS Genetics · Sep 19, 2025Peer-reviewedNeuroscience