Pathobiology of the autophagy-lysosomal pathway in the Huntington's disease brain
Martin J. Berg, Veeranna, Corrinne M. Rosa, Asok R. Kumar, Panaiyur S. Mohan, Philip H. Stavrides, Sandipkumar Darji, Deanna M. Marchionini, Dun‐Sheng Yang, Ralph A. Nixon
This study investigates the role of the autophagy-lysosomal pathway in Huntington's disease, finding that autophagic flux declines due to substrate clearance deficits in later stages.
Acta Neuropathologica Communications · Nov 7, 2025Peer-reviewedPathology