Author

Dun‐Sheng Yang

Nathan Kline Institute for Psychiatric ResearchORCID 0000-0001-9259-3015Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Pathology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Deanna M. MarchioniniiD· 2 shared Philip H. StavridesiD· 2 shared Ralph A. NixoniD· 2 shared Asok R. Kumar· 1 shared Chris N. GoulbourneiD· 1 shared Chunfeng Huo· 1 shared Corrinne M. Rosa· 1 shared James Peddy· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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2 shared papersPathology

Deanna M. MarchioniniORCID

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2 papers

Recent·Most cited

PathologyActa Neuropathologica CommunicationsPeer-reviewedNov 7, 2025

Pathobiology of the autophagy-lysosomal pathway in the Huntington's disease brain

Martin J. Berg, Veeranna, Corrinne M. Rosa…·Ralph A. Nixon

This study investigates the role of the autophagy-lysosomal pathway in Huntington's disease, finding that autophagic flux declines due to substrate clearance deficits in later stages.

15 citations

humanimaging

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PathologyeLifePeer-reviewedJan 28, 2025

mTOR inhibition in Q175 Huntington's disease model mice facilitates neuronal autophagy and mutant huntingtin clearance

Philip H. Stavrides, Chris N. Goulbourne, James Peddy…·Dun‐Sheng Yang

This study shows that mTOR inhibition in HD model mice improves autophagy and reduces mutant huntingtin accumulation.

8 citations

mouseproteomics

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