Lysine specific demethylase 1 (LSD1) regulates host alpha-ketoglutarate levels to modulate lipid peroxidation during Mycobacterium tuberculosis infection
Awantika Shah, Aakash Chandramouli, Atheena Abhayakumar, Raju S Rajmani, Siddhesh S. Kamat, Kithiganahalli Narayanaswamy Balaji
This study shows LSD1 regulates host alpha-ketoglutarate levels, modulating lipid peroxidation and mycobacterial survival during tuberculosis infection.
bioRxiv · Apr 22, 2026 · PreprintImmunology