Author

Ator Ashoti

Hubrecht Institute for Developmental Biology and Stem Cell Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:perturbation response prediction· 1 Assay:scRNA-seq· 1 Approach:statistical model· 1

Frequent Co-Authors

Anna AlemanyiD· 2 shared Niels GeijseniD· 2 shared Fanny SageiD· 1 shared Federica PiccioniiD· 1 shared Francesco LimoneiD· 1 shared Judith Vivié· 1 shared Kevin C. EgganiD· 1 shared Melissa van Kranenburg· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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2 shared papersMolecular Biology

Anna AlemanyORCID

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2 papers

Recent·Most cited

DUX4 induces a homogeneous sequence of molecular changes, culminating in the activation of a stem-cell-like transcriptional network and induction of apoptosis in somatic cells

Ator Ashoti, Anna Alemany, Fanny Sage, Niels Geijsen

The paper investigates how DUX4 induces a sequence of transcriptional changes leading to apoptosis in somatic cells by activating a stem-cell-like network.

bioRxiv · May 4, 2021 · PreprintMolecular Biology

A genome-wide CRISPR/Cas phenotypic screen formodulators of DUX4 cytotoxicity reveals screen complications

Ator Ashoti, Francesco Limone, Melissa van Kranenburg, Anna Alemany, Mirna Lilian Baak, Judith Vivié, Federica Piccioni, Menno P. Creyghton, Kevin C. Eggan, Niels Geijsen

The paper performs a genome-wide CRISPR/Cas9 screen to identify modulators of DUX4 cytotoxicity in FSHD but finds no key effectors other than DUX4 itself.

bioRxiv · Jul 27, 2020 · PreprintMolecular Biology