Author

Melissa van Kranenburg

Hubrecht Institute for Developmental Biology and Stem Cell Research

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genetics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:CRISPR screen· 1 Assay:Hi-C· 1 Organism:human· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Amin AllahyariD· 1 shared Anna AlemanyiD· 1 shared Ator Ashoti· 1 shared Benjamin D. RowlandiD· 1 shared Britta A. M. BouwmaniD· 1 shared Carlo VermeuleniD· 1 shared Elzo de WitiD· 1 shared Federica PiccioniiD· 1 shared

Activity by Year

2018-2020 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperGenetics

Amin AllahyarORCID

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2 papers

Recent·Most cited

A genome-wide CRISPR/Cas phenotypic screen formodulators of DUX4 cytotoxicity reveals screen complications

Ator Ashoti, Francesco Limone, Melissa van Kranenburg, Anna Alemany, Mirna Lilian Baak, Judith Vivié, Federica Piccioni, Menno P. Creyghton, Kevin C. Eggan, Niels Geijsen

The paper performs a genome-wide CRISPR/Cas9 screen to identify modulators of DUX4 cytotoxicity in FSHD but finds no key effectors other than DUX4 itself.

bioRxiv · Jul 27, 2020 · PreprintMolecular Biology

Locus-Specific Enhancer Hubs And Architectural Loop Collisions Uncovered From Single Allele DNA Topologies

Amin Allahyar, Carlo Vermeulen, Britta A. M. Bouwman, Peter H.L. Krijger, Marjon J.A.M. Verstegen, Geert Geeven, Melissa van Kranenburg, Mark Pieterse, Roy Straver, Judith H.I. Haarhuis, Kees Jalink, Hans Teunissen, Ivo Renkens, Wigard P. Kloosterman, Benjamin D. Rowland, , Wouter L. de Laat

The paper introduces a new 3C method, MC-4C, to study multi-way DNA conformations and reveals cooperative and competitive chromatin interactions, including enhancer hubs and loop collisions.

Nature Genetics · Jul 6, 2018Peer-reviewedGenetics